Changes in the impact and control of the grey squirrel (Sciurus carolinensis) as determined from regional surveys in Great Britain

Mayle, B., Broome, A

The use of DiazaConTM to limit fertility in grey squirrels

Mayle, B., Ferryman, M., Peace, A., Yoder, C.A., Miller, L.A., Cowan, D

The impacts of feral boar on woodland flora and fauna in Great Britain

Mayle, B., Harmer, R., Kewitt, A., Peace, A., Straw, N., Williams, D., Upson, M

Interaction-induced stabilization of circular Rydberg atoms

We discuss a candidate solution for the controlled trapping and manipulation of two individual Rydberg atoms by means of a magnetic Ioffe-Pritchard trap that is superimposed by a constant electric field. In such a trap Rydberg atoms experience a permanent electric dipole moment that can be of the order of several hundred Debye. The interplay of electric dipolar repulsion and three dimensional magnetic confinement leads to a well controllable equilibrium configuration with tunable trap frequency and atomic distance. We thoroughly investigate the trapping potentials and analyze the interaction-induced stabilization of two such trapped Rydberg atoms. Possible limitations and collapse scenarios are discussed.Comment: 18 pages, 5 figure

A Fresh Look at Axions and SN 1987A

We re-examine the very stringent limits on the axion mass based on the strength and duration of the neutrino signal from SN 1987A, in the light of new measurements of the axial-vector coupling strength of nucleons, possible suppression of axion emission due to many-body effects, and additional emission processes involving pions. The suppression of axion emission due to nucleon spin fluctuations induced by many-body effects degrades previous limits by a factor of about 2. Emission processes involving thermal pions can strengthen the limits by a factor of 3-4 within a perturbative treatment that neglects saturation of nucleon spin fluctuations. Inclusion of saturation effects, however, tends to make the limits less dependent on pion abundances. The resulting axion mass limit also depends on the precise couplings of the axion and ranges from 0.5x10**(-3) eV to 6x10**(-3) eV.Comment: 32 latex pages, 13 postscript figures included, uses revtex.sty, submitted to Physical Review

Engagement of nucleotide-binding oligomerization domain-containing protein 1 (NOD1) by receptor-interacting protein 2 (RIP2) is insufficient for signal transduction.

Following activation, the cytoplasmic pattern recognition receptor nucleotide-binding oligomerization domain-containing protein 1 (NOD1) interacts with its adaptor protein receptor-interacting protein 2 (RIP2) to propagate immune signaling and initiate a proinflammatory immune response. This interaction is mediated by the caspase recruitment domain (CARD) of both proteins. Polymorphisms in immune proteins can affect receptor function and predispose individuals to specific autoinflammatory disorders. In this report, we show that mutations in helix 2 of the CARD of NOD1 disrupted receptor function but did not interfere with RIP2 interaction. In particular, N43S, a rare polymorphism, resulted in receptor dysfunction despite retaining normal cellular localization, protein folding, and an ability to interact with RIP2. Mutation of Asn-43 resulted in an increased tendency to form dimers, which we propose is the source of this dysfunction. We also demonstrate that mutation of Lys-443 and Tyr-474 in RIP2 disrupted the interaction with NOD1. Mapping the key residues involved in the interaction between NOD1 and RIP2 to the known structures of CARD complexes revealed the likely involvement of both type I and type III interfaces in the NOD1·RIP2 complex. Overall we demonstrate that the NOD1-RIP2 signaling axis is more complex than previously assumed, that simple engagement of RIP2 is insufficient to mediate signaling, and that the interaction between NOD1 and RIP2 constitutes multiple CARD-CARD interfaces.This work was funded by a Wellcome Trust Career Development Fellowship (WT085090MA) to TPM. TAK is supported by the German Research Foundation (DFG), grant SFB670 and acknowledges support by the Koeln Fortune Program / Faculty of Medicine, University of CologneThis is the final published version. It's also available from the Journal of Biological Chemistry website at http://www.jbc.org/content/289/33/22900.abstract

Instabilities in neutrino-plasma density waves

One examines the interaction and possible resonances between supernova neutrinos and electron plasma waves. The neutrino phase space distribution and its boundary regions are analyzed in detail. It is shown that the boundary regions are too wide to produce non-linear resonant effects. The growth or damping rates induced by neutrinos are always proportional to the neutrino flux and $G_{{\rm F}}^{2}$.Comment: 9 pages, a few words modified to match PRD publicatio

Aerodynamic Tests of the Space Launch System for Database Development

The Aerosciences Branch (EV33) at the George C. Marshall Space Flight Center (MSFC) has been responsible for a series of wind tunnel tests on the National Aeronautics and Space Administration's (NASA) Space Launch System (SLS) vehicles. The primary purpose of these tests was to obtain aerodynamic data during the ascent phase and establish databases that can be used by the Guidance, Navigation, and Mission Analysis Branch (EV42) for trajectory simulations. The paper describes the test particulars regarding models and measurements and the facilities used, as well as database preparations

Femtolensing and Picolensing by Axion Miniclusters

Non-linear effects in the evolution of the axion field in the early Universe may lead to the formation of gravitationally bound clumps of axions, known as ``miniclusters.'' Minicluster masses and radii should be in the range $M_{\rm mc}\sim10^{-12} M_\odot$ and $R_{\rm mc} \sim 10^{10}$cm, and in plausible early-Universe scenarios a significant fraction of the mass density of the Universe may be in the form of axion miniclusters. If such axion miniclusters exist, they would have the physical properties required to be detected by ``femtolensing.''Comment: 7 pages plus 2 figures (Fig.1 avalible upon request), LaTe